Clinical evaluation of alkaline ionized water for abdominal
complaints: Placebo controlled double blind tests
Hirokazu Tashiro, Tetsuji Hokudo, Hiromi Ono, Yoshihide Fujiyama,
Tadao Baba (National Ohkura Hospital, Dept. of Gastroenterology;
Institute of Clinical Research, Shiga University of Medical
Science, Second Dept. of Internal Medicine
"Effect of alkaline ionized water on abdominal complaints
was evaluated by placebo controlled double blind tests. Overall
scores of improvement using alkaline ionized water marked higher
than those of placebo controlled group, and its effect proved
to be significantly higher especially in slight symptoms of
chronic diarrhea and abdominal complaints in cases of general
malaise. Alkaline ionized water group did not get interrupted
in the course of the test, nor did it show serious side effects
nor abnormal test data. It was confirmed that alkaline ionized
water is safer and more effective than placebos.
Summary
Effect of alkaline ionized water on abdominal complaints
was clinically examined by double blind tests using
clean water
as placebo. Overall improvement rate was higher for alkaline
ionized water group than placebo group and the former
proved to be significantly more effective than the other especially
in cases of slight symptoms. Examining improvement rate
for each case of chronic diarrhea, constipation and
abdominal
complaints, alkaline ionized water group turned out to
be
more effective than placebo group for chronic diarrhea,
and abdominal
complaints.
The test was stopped in one case of chronic
diarrhea, among placebo group due to exacerbation,
whereas alkaline
ionized water group did not stop testing without
serious side effects
or abnormal test data in all cases.
It was confirmed
that alkaline ionized water is more effective than clean
water against chronic
diarrhea, abdominal complaints and overall improvement
rate (relief of abdominal complaints) and safer than
clean
water.
Introduction
Since the approval of alkaline ionized water electrolyzers
by Pharmaceutical Affairs Law in 1966 for its
antacid effect and efficacy against gastrointestinal disorders
including
hyperchylia, indigestion, abnormal gastrointestinal
fermentation and chronic
diarrhea, they have been extensively used among
patients.
However, medical and scientific evaluation
of their
validity is not established. In our study,
we examined
clinical
effect of alkaline ionized water on gastrointestinal
disorders across
many symptoms in various facilities. Particularly,
we studied safety and usefulness of alkaline
ionized water
by doubleblind
tests using clean water as a control group.
Test subjects and methods
163 patients (34 men, 129 women,
age 21 to 72, average 38.6 years old) of indigestion,
abnormal
gastrointestinal
fermentation
(with abnormal gas emission and rugitus)
and abdominal complaints caused by irregular dejection
(chronic
diarrhea, or constipation)
were tested as subjects with good informed
consent.
Placebo controlled double blind
tests were conducted
using alkaline
ionized water and clean water at multiple
facilities. An alkaline ionized water electrolyzer sold
commercially was
installed
with a pump driven calcium dispenser
in each of the subject homes. Tested alkaline ionized
water
had
pH at 9.5 and
calcium concentration at 30ppm.
Each
subject in placebo group used
a water purifier that has the same
appearance as the electrolyzer and produces clean
water.
The tested equipment was randomly assigned
by a controller who scaled off the
key code which
was
stored safely
until the tests were completed and
the seal was opened again.
Water samples were given to
each patient in the amount of 200ml in the morning
with the
total
of 50Oml or
more per
day for
a month. Before and after the tests,
blood, urine and stool were tested
and a log was
kept on the
subjective symptoms,
bowel movements and accessory symptoms.
After the tests,
the results were analyzed based
on the log and the test data.
Conclusion
As a result of double blind clinical tests of alkaline ionized
water and clean water, alkaline ionized water was proved
to be more effective than clean water against chronic
diarrhea, abdominal complaints (dyspepsia) and overall
improvement
rate
(relief from abdominal complaints). Also, safety of alkaline
ionized water was confirmed which clinically verifies its
usefulness.
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